Changes in Neural Reward Processing Following Amplification of Positivity Treatment for Depression and Anxiety: Outcomes From a Randomized Waitlist Controlled Trial

A waitlist-controlled trial of group cognitive behavioural therapy for depression and anxiety in Parkinson’s disease

BACKGROUND The aim of this study was to evaluate the efficacy of a group Cognitive Behavioural Therapy (CBT) treatment for depression and anxiety in Parkinson's disease (PD). METHODS A waitlist-controlled trial design was used. Eighteen adults with PD and a comorbid DSM-IV-TR diagnosis of depression and/or anxiety were randomised to either Intervention (8-week group CBT treatment) or Waitlist...

Effect of Statin Treatment on COVID-19 Patients’ Outcomes: A Randomized Double-blind Controlled Clinical Trial

Background: Statins may be protective against viral infection and have been suggested for the treatment of coronavirus disease 2019 (COVID-19).  Objective: In this study, we aimed to evaluate the effect of atorvastatin on COVID-19 patients. Methods: Our study is a randomized double-blind controlled clinical trial that constitutes a population of COVID-19 patients admitted to Bu-Ali Sina Hospi...

Comparing the Outcomes of Minimal Incision and Double Incision in Treatment of Carpal Tunnel Syndrome: A Randomized Controlled Trial

Background and purpose: Carpal tunnel syndrome is the most prevalent neuropathy caused by trapping and median nerve compression in the wrist. This study aimed at comparing the effects of minimal incision and double incision in treatment of patients with carpal tunnel syndrome. Materials and methods: This randomized controlled trial was performed in 50 patients with carpal tunnel syndrome atten...

Stepped care treatment for depression and anxiety in primary care. a randomized controlled trial

BACKGROUND Depressive and anxiety disorders are common in general practice but not always treated adequately. Introducing stepped care might improve this. In this randomized trial we examined the effectiveness of such a stepped care model. METHODS The study population consisted of primary care attendees aged 18-65 years with minor or major DSM-IV depressive and/or anxiety disorders, recruited...

Stepped Care Treatment for Depression and Anxiety in Primary Care: A Randomized Controlled Trial